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Cardionil Isosorbide Mononitrate

The active ingredient in CARDIONIL 20mg is Isosorbide-5-mononitrate. Each capsule contains Isosorbide-5-mononitrate 20mg (DCI)

  1. WHAT CARDIONIL 20mg IS and FOR WHAT PURPOSE IS PRESCRIBED: CARDIONIL 20 mg is presented as capsules for oral administration, in packages containing 30 or 60 capsules. It is a medicine that belongs to the group of nitrates and is indicated for the preventive treatment of angina pectoris.

    The angina pectoris is a consequence of the imbalance between the oxygen needs of the cardiac muscle and the quantity of oxygen contributed to this muscle by the blood that steams in the coronary arteries.

    The nitrates and among of them the isosorbide 5-mononitrate, that has a prolonged action:

  1. consequently reduces to the work of the heart and the oxygen needs of the cardiac muscle;

  2. increases to the arrival of oxygen to this muscle by exerting a powerful action of the coronary arteries.

This medicine is used for prophylaxis and treatment of angina pectoris.

  1.  BEFORE TAKING CARDIONIL 20 mg (Do not take CARDIONIL 20 mg):

  • If you have hypersensitivity to any of the components of the product.

  • If you have serious cardiovascular pathology (shock, collapse, serious hypotension, certain types of myocardium infarct) nor in case of marked anaemia, cerebral traumatism or cerebral haemorrhage

  • If you are pregnant or in lactation period. You should not take it during the first trimester of the pregnancy except prescribed by your doctor. It is not known if the medicine can be transferred to maternal milk.

  • The simultaneous administration of CARDIONIL and some antihypertension medications and phenothiazine can increase the reducing effect of the arterial pressure, mainly in people advanced in years.

Special precautions with CARDIONIL 20mg:
  • Do not take alcohol during the treatment, since it can diminish the reaction capacity.

  • Inform your doctor of all your present and past problems and of any hypersensitivity that you undergo.

  • CARDIONIL is not indicated for children.

Pregnancy

You should not take it during the first trimester of the pregnancy except prescribed by your doctor.

Lactation

It is not known if the medicine can be transferred to maternal milk.

People advanced in years

It is advisable to realize the administration to seated patient.

Children

CARDIONIL is not indicated for children.

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  1. DIRECTIONS FOR USE

    Follow these instructions unless your doctor has given you others.  Remember taking the medicine. Your doctor will advise of duration of therapy with CARDIONIL.  Do not interrupt therapy sooner sooner otherwise desired effect will not be achieved.

    Do not continue treatment beyond period prescribed by your doctor. It will have to respect strictly the dosage without diminishing nor increasing it except by the instruction of your doctor.  The posology of isosorbide 5-mononitrate is strictly individual and your doctor has recommended you the one that is considered more suitable. The most usual dose is two capsules/day. In order to avoid the tolerance to the medicine, the administration will be made on irregular intervals between 7 and 17 hours
    .

    It is possible that your doctor prescribes this medicine to you in progressivel increasing doses until reaching the most effective and better tolerated one in your individual case.  It is advisable, mainly at the beginning of the treatment, when high doses are used or in people advanced in years that the administration of the medicine is realized to a seated patient  The CARDIONIL capsules have to be taken whole with a glass of water. Your doctor will indicate the duration of the treatment with CARDIONIL 20mg

    If you take more CARDIONIL 20mg than required: immediately contact your doctor or pharmacist.  In case of overdose or incidental ingestion, call the local poison control centre.  The main symptom that could appear is a reduction of the arterial pressure. In order to correct it, usually it is enough with maintaining the patient seated with legs raised up. In any case, consult your doctor immediately: it can be necessary to wash the stomach or to get treatment in a specialized centre.

    If you forgot to take CARDIONIL 20mg: do not take a double dose to compensate forgotten doses. As soon as you are conscious of the forgetfulness, continue with treatment, administering the medicine like usual.

  1. POTENTIAL ADVERSE EFFECTS

    Like any other medicine, adverse effects may occur during the treatment with CARDIONIL

    In general isosorbide-5-mononitrate is suitably tolerated. In certain cases, especially with high doses or at the beginning of the treatment, there can be a reduction of the arterial pressure related to the change of position (getting up, standing on ones foot)

    Other secondary effects that can appear are headache, reddening or local heat sensation, palpitations, nauseas, fatigue, this will usually slow down by continuing the treatment or diminishing the dose.

    In rare cases, cutaneous eruptions could take place. If any other adverse reaction previously not described is observed, see your doctor or pharmacist.

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  1.  CARDIONIL 20mg STORAGE

Does not require any special storage conditions.

Expiry date

Do not use CARDIONIL 20mg after the expiration date written on the package.

Keep CARDIONIL 20mg out of reach of children

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